Tubulysin C
Cat. No.:YN270521
产品名称: | Tubulysin C |
CAS No.: | 205304-88-7 |
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分子量: | 816.02 |
分子式: | C₄₁H₆₁N₅O₁₀S |
SMILES: | O=C([C@@]([C@@H](C)CC)([H])NC([C@@H](CCCC1)N1C)=O)N(COC(CC)=O)[C@@H](C(C)C)C[C@H](C2=NC(C(N[C@H](C[C@H](C)C(O)=O)CC3=CC=C(O)C=C3)=O)=CS2)OC(C)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Tubulysin C 是一种高度细胞毒性的肽,是从粘细菌Archangium geophyra和Angiococcus disciformis中分离的。 Tubulysin 在哺乳动物细胞中显示出极其有效的细胞毒活性,包括多药耐药细胞系,IC50值在较低的纳摩尔范围内。 Tubulysin C 是一种具有细胞毒性活性微管溶素,抑制微管蛋白聚合并导致细胞周期停滞和凋亡。 |
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