3'-Hydroxypterostilbene
Cat. No.：YN270555
| 产品名称: | 3'-Hydroxypterostilbene |
| CAS No.: | 475231-21-1 |
| Chemical Name: | 4-[(1E)-2-(3,5-Dimethoxyphenyl)ethenyl]-1,2-benzenediol; 3'-Hydroxypterostilbene |
| Synonyms: | 3’-羟基紫檀茋 |
| 分子量: | 272.30 |
| 分子式: | C₁₆H₁₆O₄ |
| SMILES: | COC1=CC(/C=C/C2=CC=C(O)C(O)=C2)=CC(OC)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 3'-Hydroxypterostilbene，一种天然紫檀芪类似物，通过诱导细胞凋亡 (apoptosis) 和自噬 (autophagy)，有效抑制人结肠癌细胞的生长 (对 COLO 205，HCT-116 和 HT-29 细胞的 IC50分别为 9.0，40.2 和 70.9 μM)。3'-Hydroxypterostilbene 抑制 PI3K/Akt/mTOR/p70S6K 和 p38MAPK 途径并激活 ERK1/2，JNK1/2 MAPK途径。 |
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Majeed, M., et al.: PLoS One, 12, e0172770 (2017)
