9-Methoxycamptothecin
Cat. No.:YN270556
产品名称: | 9-Methoxycamptothecin |
CAS No.: | 39026-92-1 |
Chemical Name: | (4S)-4-Ethyl-4-hydroxy-10-methoxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 9-Methoxycamptothecin; 9-Methoxycamptothecine; NSC 176323; |
Synonyms: | |
分子量: | 378.38 |
分子式: | C₂₁H₁₈N₂O₅ |
SMILES: | CC[C@@]1(C2=C(COC1=O)C(N3C(C4=NC5=CC=CC(OC)=C5C=C4C3)=C2)=O)O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 9-Methoxycamptothecin (MCPT),是从Nothapodytes foetida中分离得到的,通过抑制拓扑异构酶发挥抗肿瘤活性。9-Methoxycamptothecin (MCPT) 具有强效的诱导G2/M期细胞和癌细胞凋亡的作用。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Jain, S. et al.: Bioorg. Med. Chem., Lett. 24, 3146 (2014)