Alkannin
Cat. No.：YN270557
| 产品名称: | Alkannin |
| CAS No.: | 517-88-4 |
| Chemical Name: | 5,8-dihydroxy-2-[(1S)-1-hydroxy-4-methyl-3-penten-1-yl]-1,4-naphthalenedione |
| Synonyms: | 左旋紫草素 |
| 分子量: | 288.30 |
| 分子式: | C₁₆H₁₆O₅ |
| SMILES: | OC1=C2C(C(C=C([C@H](C/C=C(C)/C)O)C2=O)=O)=C(O)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Alkannin，在alkanna tinctoria中发现，用作食品着色剂。Alkannin 具有抗癌活性，抑制细胞周期，诱导细胞凋亡。Alkannin 在 Rho 激酶途径中改善肝脏炎症。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Chen, J., Xie, J., Jiang, Z., et al.Shikonin and its analogs inhibit cancer cell glycolysis by targeting tumor pyruvate kinase-M2Oncogene30(42),4297-4306(2011)
Huu Tung, N., Du, G.-J., Wang, C.-Z., et al.Naphthoquinone components from Alkanna tinctoria (L.) Tausch show significant antiproliferative effects on human colorectal cancer cellsPhytother. Res.27(1),66-70(2013)
Yoshihisa, Y., Hassan, M.A., Furusawa, Y., et al.Alkannin, HSP70 inducer, protects against UVB-induced apoptosis in human keratinocytesPLoS One7(10),e47903(2012)
Shen, C.-C., Syu, W.-J., Li, S.-Y., et al.Antimicrobial activities of naphthazarins from Arnebia euchromaJ. Nat. Prod.65(12),1857-1862(2002)
Assimopoulou, A.N., and Papageorgiou, V.P.Radical scavenging activity of Alkanna tinctoria root extracts and their main constituents, hydroxynaphthoquinonesPhytother. Res.19(2),141-147(2005)
