Bacopaside II
Cat. No.：YN270558
CAS No. ：382146-66-9
| 产品名称: | Bacopaside II |
| CAS No.: | 382146-66-9 |
| Chemical Name: | (1S,2R,4aR,6aS,6bR,8aR,10S,12aR,12bR,14aR,14bS)-hexadecahydro-1-hydroxy-1,6b,9,9,12a-pentamethyl-2-(2-methyl-1-propen-1-yl)-4a,6a-methano-1H,6H-phenanthro[2,1-d]pyrano[2,3-b]pyran-10-yl O-α-L-arabinofuranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-β-D-glucopy |
| Synonyms: | |
| 分子量: | 929.10 |
| 分子式: | C₄₇H₇₆O₁₈ |
| SMILES: | C[C@]12[C@@]34[C@@](CC[C@]1([H])[C@@]5([C@@](C(C)([C@@H](O[C@@]6([H])[C@@H]([C@H]([C@H](O)[C@@H](CO)O6)O[C@]7([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]7O)CO)O[C@]8([H])O[C@@H](CO)[C@H](O)[C@H]8O)CC5)C)([H])CC2)C)([H])[C@]9([H])[C@@](OC4)(OC[C@@H](/C=C(C)\C)[C@@] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Bacopaside II 是一种药用植物Bacopa monnieri的提取物，它阻断Aquaporin-1 (AQP1)水通道并阻碍表达 AQP1 的细胞迁移。Bacopaside II 还会诱导细胞周期停滞和细胞凋亡。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Bhardwaj, P., Jain, C.K., and Mathur, A.Comparative evaluation of four triterpenoid glycoside saponins of bacoside A in alleviating sub-cellular oxidative stress of N2a neuroblastoma cellsJ. Pharm. Pharmacol.70(11),1531-1540(2018)
Zhou, Y., Shen, Y.-H., Zhang, C., et al.Triterpene saponins from Bacopa monnieri and their antidepressant effects in two mice modelsJ. Nat. Prod.70(4),652-655(2007)
Palethorpe, H.M., Tomita, Y., Smith, E., et al.The aquaporin 1 inhibitor bacopaside II reduces endothelial cell migration and tubulogenesis and induces apoptosisInt. J. Mol. Sci.19(3),E653(2018)
Peng, L., Zhou, Y., Kong, D.Y., et al.Antitumor activities of dammarane triterpene saponins from Bacopa monnieraPhytother. Res.24(6),864-868(2010)
