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T-​2 Toxin

Cat. No.:YN270572

  • CAS No. :21259-20-1

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: T-​2 Toxin
      CAS No.: 21259-20-1
      Chemical Name: (3α,4β,8α)-12,13-epoxy-4,15-diacetate 8-(3-methylbutanoate)trichothec-9-ene-3,4,8,15-tetrol
      Synonyms:T-2 Mycotoxin
      分子量:468.54
      分子式:C₂₄H₃₆O₉
      SMILES:CC12C3(CO3)[C@@](O[C@@](/C=C(C)\[C@@H](OC(CC(C)C)=O)C)([H])[C@H]2COC(C)=O)([H])[C@H](O)[C@H]1OC(C)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: T-2 Toxin (T-2 Mycotoxin) 是饲料和谷物中的各种镰刀菌种产生的真菌毒素。小大鼠中T-2 Toxin 的LD50值分别为 5.2 和1.5 mg/kg BWa。T-2 Toxin (T-2 Mycotoxin) 可以转化为多种代谢产物,动物中T-2 Toxin 的典型代谢产物是 HT-2 toxin 和 T-2-triol,均为水解产物。_x000D_ T-2 Toxin (T-2 Mycotoxin) 是一种抑制肽基转移酶 (60s ribosomal 亚基) 结合和蛋白质合成的抑
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Doi, K., and Uetsuka, K.Mechanisms of mycotoxin-induced neurotoxicity through oxidative stress-associated pathwaysInt. J. Mol. Sci.12(8),5213-5237(2011)

      Seeboth, J., Solinhac, R., Oswald, I.P., et al.The fungal T-2 toxin alters the activation of primary macrophages induced by TLR-agonists resulting in a decrease of the inflammatory response in the pigVet. Res.43(1),1-18(2012)

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