T-2 Toxin
Cat. No.:YN270572
CAS No. :21259-20-1
产品名称: | T-2 Toxin |
CAS No.: | 21259-20-1 |
Chemical Name: | (3α,4β,8α)-12,13-epoxy-4,15-diacetate 8-(3-methylbutanoate)trichothec-9-ene-3,4,8,15-tetrol |
Synonyms: | T-2 Mycotoxin |
分子量: | 468.54 |
分子式: | C₂₄H₃₆O₉ |
SMILES: | CC12C3(CO3)[C@@](O[C@@](/C=C(C)\[C@@H](OC(CC(C)C)=O)C)([H])[C@H]2COC(C)=O)([H])[C@H](O)[C@H]1OC(C)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | T-2 Toxin (T-2 Mycotoxin) 是饲料和谷物中的各种镰刀菌种产生的真菌毒素。小大鼠中T-2 Toxin 的LD50值分别为 5.2 和1.5 mg/kg BWa。T-2 Toxin (T-2 Mycotoxin) 可以转化为多种代谢产物,动物中T-2 Toxin 的典型代谢产物是 HT-2 toxin 和 T-2-triol,均为水解产物。_x000D_ T-2 Toxin (T-2 Mycotoxin) 是一种抑制肽基转移酶 (60s ribosomal 亚基) 结合和蛋白质合成的抑 |
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Doi, K., and Uetsuka, K.Mechanisms of mycotoxin-induced neurotoxicity through oxidative stress-associated pathwaysInt. J. Mol. Sci.12(8),5213-5237(2011)
Seeboth, J., Solinhac, R., Oswald, I.P., et al.The fungal T-2 toxin alters the activation of primary macrophages induced by TLR-agonists resulting in a decrease of the inflammatory response in the pigVet. Res.43(1),1-18(2012)