RGD peptide (GRGDNP)
Cat. No.：YN270607
| 产品名称: | RGD peptide (GRGDNP) |
| CAS No.: | 114681-65-1 |
| Chemical Name: | glycyl-L-arginylglycyl-L-α-aspartyl-L-asparaginyl-L-proline |
| Synonyms: | H-甘氨酰-精氨酰-甘氨酰-天冬氨酰-天冬酰胺酰-脯氨酸-OH,RGD peptide GRGDNP(2TFA),RGD peptide GRGDNP |
| 分子量: | 614.61 |
| 分子式: | C₂₃H₃₈N₁₀O₁₀ |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | RGD peptide (GRGDNP) 作为整合素-配体相互作用的抑制剂，在细胞黏附、迁移、生长和分化中发挥重要作用。RGD peptide (GRGDNP) 通过激活构象变化促进细胞凋亡，从而增强caspase-3的活化。 |
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Ruoslahti, E., and Öbrink, B.Common principles in cell adhesionExp. Cell Res.227(1),1-11(1996)
Buckley, C.D., Pilling, D., Henriquez, N.V., et al.RGD peptides induce apoptosis by direct caspase-3 activationNature397(6719),534-539(1999)
Adderley, S.R., and Fitzgerald, D.J.Glycoprotein IIb/IIIa antagonists induce apoptosis in rat cardiomyocytes by caspase-3 activationJ. Biol. Chem.275(8),5760-5766(2000)
