O6-Benzylguanine
Cat. No.：YN270618
CAS No. ：19916-73-5
| 产品名称: | O6-Benzylguanine |
| CAS No.: | 19916-73-5 |
| Chemical Name: | 6-(phenylmethoxy)-9H-purin-2-amine |
| Synonyms: | O6-BG |
| 分子量: | 241.25 |
| 分子式: | C₁₂H₁₁N₅O |
| SMILES: | NC(N=C1OCC2=CC=CC=C2)=NC3=C1NC=N3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | O6-Benzylguanine 是鸟嘌呤类似物，是 DNA 修复酶 O6 烷基鸟嘌呤DNA烷基转移酶(MGMT/AGT)抑制剂。O6-Benzylguanine 作为 AGT 底物，将其苄基转移到 AGT 半胱氨酸残基上，从而不可逆地灭活 AGT 并阻止 DNA 修复。O6-Benzylguanine 诱导肿瘤细胞凋亡，具有抗肿瘤活性。 |
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