(E)-Ferulic acid-d
Cat. No.：YN270748
| 产品名称: | (E)-Ferulic acid-d |
| CAS No.: | 388082-78-8 |
| Chemical Name: | N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-Quinazolinamine 4-methylbenzenesulfonate hydrate; N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)eth |
| Synonyms: | 二甲苯磺酸拉帕替尼; GW572016 ditosylate monohydrate; GW2016 ditosylate monohydrate |
| 分子量: | 943.47 |
| 分子式: | C43H44ClFN4O11S3 |
| SMILES: | ClC1=C(C([H])=C([H])C(=C1[H])N([H])C1C2=C(C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C(C([H])([H])N([H])C([H])([H])C([H])([H])S(C([H])([H])[H])(=O)=O)O2)N=C([H])N=1)OC([H])([H])C1C([H])=C([H])C([H])=C(C=1[H])F |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lapatinib ditosylate monohydrate (GW572016 ditosylate monohydrate) 是一种ErbB-2和EGFR酪氨酸激酶结构域的有效抑制剂，对纯化的EGFR和ErbB-2的IC50值分别为 10.2 和 9.8 nM。 |
| IC50和靶点: | [{name:"EGFR:10.8 nM (IC50)"},{name: "ErbB2:9.2 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Erickson, G.
et al.: Tetrahedron Lett., 55, 6007 (2014)
Boyd, B.
Drugs of the Future, 30, 1225 (2005).
