AZD1152
Cat. No.:YN290029
产品名称: | AZD1152 |
CAS No.: | 722543-31-9 |
Chemical Name: | 5-[[7-[3-[Ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-1H-pyrazole-3-acetamide; AZD 1152 |
Synonyms: | Barasertib |
分子量: | 587.54 |
分子式: | C₂₆H₃₁FN₇O₆P |
SMILES: | O=C(NC1=CC=CC(F)=C1)CC2=CC(NC3=C4C=CC(OCCCN(CC)CCOP(O)(O)=O)=CC4=NC=N3)=NN2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | AZD1152 是 Barasertib-hQPA 的前体药物,是高度选择性的Aurora B抑制剂,IC50值为 0.37 nM。 |
IC50和靶点: | [{name:"Aurora B:0.37 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Wilkinson, Robert W.,et al., Clin. Cancer Res. (2007), 1, 3682.