MLN8054
Cat. No.：YN290043
CAS No. ：869363-13-3
| 产品名称: | MLN8054 |
| CAS No.: | 869363-13-3 |
| Chemical Name: | 4-[[9-chloro-7-(2,6-difluorophenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-benzoic acid |
| Synonyms: | MLN-8054;MLN 8054 |
| 分子量: | 476.86 |
| 分子式: | C₂₅H₁₅ClF₂N₄O₂ |
| SMILES: | O=C(C1=CC=C(NC2=NC3=C(CN=C(C4=C3C=CC(Cl)=C4)C5=C(F)C=CC=C5F)C=N2)C=C1)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MLN8054是高效，选择性，有口服活性的极光激酶 (aurora A) 抑制剂，IC50值为4 nM。 |
| IC50和靶点: | [{name:"Aurora A:4 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Manfredi, M.G., Ecsedy, J.A., Meetze, K.A., et al.Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinaseProc. Natl. Acad. Sci. USA104(10),4106-4111(2007)
