TAK-901
Cat. No.：YN290175
CAS No. ：934541-31-8
| 产品名称: | TAK-901 |
| CAS No.: | 934541-31-8 |
| Chemical Name: | 5-[3-(ethylsulfonyl)phenyl]-3,8-dimethyl-N-(1-methyl-4-piperidinyl)-9H-pyrido[2,3-b]indole-7-carboxamide |
| Synonyms: | TAK901 |
| 分子量: | 504.64 |
| 分子式: | C₂₈H₃₂N₄O₃S |
| SMILES: | O=C(NC1CCN(CC1)C)C2=C(C3=C(C4=CC(C)=CN=C4N3)C(C5=CC=CC(S(=O)(CC)=O)=C5)=C2)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TAK-901是多靶点的的极光激酶 (aurora)抑制剂，对极光激酶A和B的IC50值分别为21 和15 nM。 |
| IC50和靶点: | [{name:"Aurora A:21 nM (IC50)"},{name: "Aurora B:15 nM (IC50)"}] |
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| Clinical Trial: | |
| Solvent & Solubility: |
Farrell, P., Shi, L., Matuszkiewicz, J., et al.Biological characterization of TAK-901, an investigational, novel, multitargeted Aurora B kinase inhibitorMol. Cancer Ther.12(4),460-470(2013)
