ABC1183
Cat. No.：YN290564
CAS No. ：1042735-18-1
| 产品名称: | ABC1183 |
| CAS No.: | 1042735-18-1 |
| Chemical Name: | |
| Synonyms: | ABC1183; ABC-1183; ABC 1183 |
| 分子量: | 334.397 |
| 分子式: | C18H14N4Os |
| SMILES: | N#CC1=CC=C(C(C2=C(N)N=C(NC3=CC=C(C)C=C3)S2)=O)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ABC1183 是一种具有口服活性的选择性GSK3和CDK9双重抑制剂。ABC1183 作用于 GSK3β, GSK3α 和 CDK9/cyclin T1 的IC50值分别是 657 nM、327 nM、321 nM。ABC1183 具有抗炎作用，抗肿瘤活性。 |
| IC50和靶点: | [{name:"CDK9- Cyclin T1:321 nM (IC50)"},{name: "GSK-3α:327 nM (IC50)"},{name: "GSK-3β:657 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
