RVX-297
Cat. No.：YN310390
CAS No. ：1044871-04-6
| 产品名称: | RVX-297 |
| CAS No.: | 1044871-04-6 |
| Chemical Name: | |
| Synonyms: | RVX297 |
| 分子量: | 423.5 |
| 分子式: | C24H29N3O4 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | RVX-297 是一种高效、具有口服活性、对BD2有选择性的BET抑制剂。RVX-297 对 BRD2(BD2)，BRD3(BD2)，BRD4(BD2) 的IC50分别为 0.08、0.05、0.02 μM。RVX-297 抑制多种免疫细胞炎症基因的表达。RVX-297 对临床前模型急性炎症和自身免疫的有效。 |
| IC50和靶点: | [{name:"BRD2 (BD1):3.76 μM (IC50)"},{name: "BRD2 (BD2):0.08 μM (IC50)"},{name: "BRD3 (BD1):2.34 μM (IC50)"},{name: "BRD3 (BD2):0.05 μM (IC50)"},{name: "BRD4 (BD1):1.16 μM (IC50)"},{name: "BRD4 (BD2):0.02 μM (IC50)"},{name: "BRDT (BD1):2.69 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
