Pyridostatin
Cat. No.：YN290568
| 产品名称: | Pyridostatin |
| CAS No.: | 1085412-37-8 |
| Chemical Name: | 4-(2-Aminoethoxy)-N2,N6-bis[4-(2-aminoethoxy)-2-quinolinyl]-2,6-pyridinedicarboxamide |
| Synonyms: | RR82 |
| 分子量: | 596.63(free base) |
| 分子式: | C31H32N8O5.XC2Hf3O2 |
| SMILES: | C(C(NC1C=C(OCCN)C2C(N=1)=CC=CC=2)=O)1=NC(C(NC2C=C(OCCN)C3C(N=2)=CC=CC=3)=O)=CC(OCCN)=C1.C(O)(=O)C(F)(F)F |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pyridostatin (RR82) 是一种高选择性的G-quadruplexDNA稳定剂 (Kd=490 nM)。Pyridostatin 通过诱导复制和转录依赖的 DNA 损伤促进人类癌细胞生长停滞。Pyridostatin 靶向原癌基因Src。Pyridostatin 降低人乳腺癌细胞SRC蛋白水平和SRC依赖的细胞运动。 |
| IC50和靶点: | |
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McLuckie, K. et al.: J. Am. Chem. Soc., 135, 9640 (2013)
