NVP-BSK805
Cat. No.：YN310393
CAS No. ：1092499-93-8
| 产品名称: | NVP-BSK805 |
| CAS No.: | 1092499-93-8 |
| Chemical Name: | |
| Synonyms: | BSK 805; BSK-805; BSK805; NVP-BSK 805 |
| 分子量: | 490.559 |
| 分子式: | C27H28F2N6O |
| SMILES: | FC1=C(CN2CCOCC2)C(F)=CC(C3=C4N=C(C5=CN(C6CCNCC6)N=C5)C=NC4=CC=C3)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | NVP-BSK805 是一种 ATP 竞争性的JAK2抑制剂，对JAK2JH1 (JAK 同源 1)，JAK1JH1，JAK3JH1，和TYK2JH1 的IC50值分别为 0.48 nM，31.63 nM，18.68 nM 和 10.76 nM。 |
| IC50和靶点: | [{name:"JAK2 JH1:0.48 nM (IC50)"},{name: "FL JAK2 V617F:0.56 nM (IC50)"},{name: "FL JAK2 wt:0.58 nM (IC50)"},{name: "TYK2 JH1:10.76 nM (IC50)"},{name: "JAK3 JH1:18.68 nM (IC50)"},{name: "JAK1 JH1:31.63 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
