Tau tracer 1
Cat. No.：YN290577
| 产品名称: | Tau tracer 1 |
| CAS No.: | 1129540-33-5 |
| Chemical Name: | βS-(benzoyl-2,3,4,5,6-d5-amino)-αR-hydroxy-benzenepropanoic acid, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[ |
| Synonyms: | 紫杉醇 d |
| 分子量: | 859 |
| 分子式: | C47H46D5NO14 |
| SMILES: | O=C([C@H](OC(C)=O)C1=C(C)[C@@H](OC([C@H](O)[C@@H](NC(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])=O)C3=CC=CC=C3)=O)C[C@]([C@H]4OC(C5=CC=CC=C5)=O)(O)C1(C)C)[C@@]6(C)[C@@]4([H])[C@@]7(OC(C)=O)[C@H](OC7)C[C@@H]6O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Paclitaxel-d5是氘标记的紫杉醇。Paclitaxel 是一种天然抗肿瘤药，可稳定微管蛋白 (tubulin) 的聚合。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Liebmann, J.E., Cook, J.A., Lipschultz, C., et al.Cytotoxic studies of paclitaxel (Taxol) in human tumour cell linesBr. J. Cancer68(6),1104-1109(1993)
Woods, C.M., Zhu, J., McQueney, P.A., et al.Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathwayMol. Med.1(5),506-526(1995)
Wang, T.h., Wang, H.S., and Soong, Y.K.Paclitaxel-induced cell death: Where the cell cycle and apoptosis come togetherCancer88(11),2619-2628(2000)
