SD-1029
Cat. No.：YN310398
| 产品名称: | SD-1029 |
| CAS No.: | 118372-34-2 |
| Chemical Name: | 9-(3,4-dichlorophenyl)-2,7-bis[(dimethylamino)methyl]-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione, dihydrobromide |
| Synonyms: | SD1029;NSC 371488 |
| 分子量: | 639.3 |
| 分子式: | C25H30Cl2N2O3 • 2HBr |
| SMILES: | ClC1=C(Cl)C=CC(C2C3=C(CCC(CN(C)C)C3=O)OC4=C2C(C(CN(C)C)CC4)=O)=C1.Br.Br |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SD-1029 是一种JAK2/STAT3抑制剂。SD-1029 抑制STAT3核易位。SD-1029 抑制JAK2磷酸化，从而抑制STAT3激活。 |
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Duan, Z., Bradner, J.E., Greenberg, E., et al.SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocationClin. Cancer Res.12(22),6844-6852(2006)
Jiang, X., Kanda, T., Wu, S., et al.Suppression of La antigen exerts potential antiviral effects against Hepatitis A virusPLoS One9(7),e101993(2014)
Liu, Y., Liu, A., Xu, Z., et al.XZH-5 inhibits STAT3 phosphorylation and causes apoptosis in human hepatocellular carcinoma cellsApoptosis16(5),502-510(2011)
