ETP-45658
Cat. No.：YN290587
CAS No. ：1198357-79-7
| 产品名称: | ETP-45658 |
| CAS No.: | 1198357-79-7 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 311.34 |
| 分子式: | C16H17N5O2 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ETP-45658 是一种有效的PI3K抑制剂，抑制PI3Kα，PI3Kδ，PI3Kβ和PI3Kγ的IC50值分别为 22.0 nM，39.8 nM，129.0 nM 和 717.3 nM。ETP-45658 还可以抑制DNA-PK(IC50=70.6 nM) 和mTOR(IC50=152.0 nM)。ETP-45658 可用于癌症研究。 |
| IC50和靶点: | [{name:"PI3Kα:22.0 nM (IC50)"},{name: "PI3Kδ:39.8 nM (IC50)"},{name: "PI3Kβ:129.0 nM (IC50)"},{name: "PI3Kγ:717.3 nM (IC50)"},{name: "mTOR:152.0 nM (IC50)"},{name: "DNA-PK:70.6 nM (IC50)"}] |
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