YK-3-237
Cat. No.：YN290588
CAS No. ：1215281-19-8
| 产品名称: | YK-3-237 |
| CAS No.: | 1215281-19-8 |
| Chemical Name: | B-[2-methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]-boronic acid |
| Synonyms: | YK-3 237 |
| 分子量: | 372.2 |
| 分子式: | C19H21BO7 |
| SMILES: | COC1=C(OC)C(OC)=CC(C(/C=C/C2=CC(B(O)O)=C(OC)C=C2)=O)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | YK-3-237 是一种SIRT1激活剂，靶向突变体 p53。YK-3-237 抑制三阴性乳腺癌细胞的增殖。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Kong, Y., Wang, K., Edler, M.C., et al.A boronic acid chalcone analog of combretastatin A-4 as a potent anti-proliferation agentBioorg. Med. Chem.18(2),971-977(2010)
Yi, Y.W., Kang, H.J., Kim, H.J., et al.Targeting mutant p53 by a SIRT1 activator YK-3-237 inhibits the proliferation of triple-negative breast cancer cellsOncotarget4(7),984-994(2013)
