FIM-1
Cat. No.:YN310405
产品名称: | FIM-1 |
CAS No.: | 1221964-50-6 |
Chemical Name: | |
Synonyms: | |
分子量: | 362.85 |
分子式: | C23H19ClO2 |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | PS315 是 PS48 (HY-15967) 的衍生物,是一种变构性PKC抑制剂,可以与 aPKC 的 PIF 口袋结合并诱导活性位点残基 Lys111 置换。PS315 抑制PKCζ(IC50=10 μM) 和PKCη(IC50=30 μM) 的全长和催化结构域构建体。PS315 具有抗癌活性。 |
IC50和靶点: | [{name:"PKCζ:10 μM (IC50)"},{name: "PKCη:30 μM (IC50)"}] |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |