(1E)-CFI-400437 dihydrochloride
Cat. No.：YN290591
CAS No. ：1247000-76-5
| 产品名称: | (1E)-CFI-400437 dihydrochloride |
| CAS No.: | 1247000-76-5 |
| Chemical Name: | |
| Synonyms: | CFI 400437,CFI400437 |
| 分子量: | 565.5 |
| 分子式: | C29H30Cl2N6O2 |
| SMILES: | CN1CCN(CC1)C2=NC=C(C=C2)/C=C/C3=NNC4=C3C=CC(=C4)/C=C/5\C6=C(C=CC(=C6)OC)NC5=O.Cl.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | (1E)-CFI-400437 dihydrochloride 是一种有效的PLK4(IC50= 0.6 nM)，并对 PLK 家族的其他成员有选择性 (>10 μM)。(1E)-CFI-400437 dihydrochloride 抑制 Aurora A、 Aurora B、KDR和FLT-3，IC50分别为 0.37、0.21、0.48 和 0.18 μM。具有抗增殖活性。 |
| IC50和靶点: | [{name:"PLK4:0.6 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
