Chiauranib
Cat. No.：YN290592
CAS No. ：1256349-48-0
| 产品名称: | Chiauranib |
| CAS No.: | 1256349-48-0 |
| Chemical Name: | |
| Synonyms: | Ibcasertib; CS2164 |
| 分子量: | 435.47 |
| 分子式: | C27H21N3O3 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Chiauranib (CS2164) 是一种针对肿瘤血管生成的具有口服活性的多靶点抑制剂。Chiauranib 有效抑制血管生成相关激酶 (VEGFR1，VEGFR2，VEGFR3，PDGFRα和c-Kit)，有丝分裂相关激酶Aurora B和慢性炎症相关激酶CSF-1R，IC50值为 1-9 nM。Chiauranib 具有很强的抗癌作用。 |
| IC50和靶点: | [{name:"Flt-1:8 nM (IC50)"},{name: "KDR:7 nM (IC50)"},{name: "Flt-4:9 nM (IC50)"},{name: "PDGFRα:1 nM (IC50)"},{name: "c-Kit:4 nM (IC50)"},{name: "Aurora B:9 nM (IC50)"},{name: "PDGFRβ:93 nM (IC50)"},{name: "CSF-1R:7 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
