Ibezapolstat
Cat. No.:YN290598
CAS No. :1275582-97-2
产品名称: | Ibezapolstat |
CAS No.: | 1275582-97-2 |
Chemical Name: | ACX-362E; |
Synonyms: | ACX-362E; GLS-362E |
分子量: | 190.13 |
分子式: | C8H7NaO4 |
SMILES: | CC([C-](C(O1)=O)C(C=C1C)=O)=O.[Na+] |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Ibezapolstat (ACX-362E) 是一种首创的,具有口服活性的 DNA 聚合酶 IIIC( DNA pol IIIC)的抑制剂,被开发用于艰难梭菌感染 (CDI) 的研究。Ibezapolstat 具有广谱的抗艰难梭菌活性,在体外对临床分离的 104 种菌株作用的MIC范围为1-8 μg/mL。 |
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Kelley, J.L., et al.: J. Med. Chem., 31, 2001 (1988), Garcia-Echeverria, C., et al.: Med. Res. Rev., 20, 28 (2000)