Trilaciclib
Cat. No.：YN290613
CAS No. ：1374743-00-6
| 产品名称: | Trilaciclib |
| CAS No.: | 1374743-00-6 |
| Chemical Name: | 7',8'-Dihydro-2'-[[5-(4-methyl-1-piperazinyl)-2-pyridinyl]amino]spiro[cyclohexane-1,9'(6'H)-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidin]-6'-one; 2'-[[5-(4-Methylpiperazin-1-yl)pyridin-2-yl]amino}-7',8'-dihydro-6'H-spiro[cyclohexane-1,9'-pyrazino[1',2':1,5] |
| Synonyms: | G1T28 |
| 分子量: | 446.548 |
| 分子式: | C24N8OH30 |
| SMILES: | O=C1NCC2(N3C1=CC4=CN=C(NC5=NC=C(N6CCN(C)CC6)C=C5)N=C43)CCCCC2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Trilaciclib 是CDK4/6的抑制剂，对于CDK4和CDK6的IC50值分别为 1 nM 和 4 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Bisi, J. E. et al.: Mol Cancer Ther. 2016 May
15(5):783-93
