Senaparib
Cat. No.:YN290617
CAS No. :1401682-78-7
产品名称: | Senaparib |
CAS No.: | 1401682-78-7 |
Chemical Name: | 5-fluoro-1-[[4-fluoro-3-[[4-(2-pyrimidinyl)-1-piperazinyl]carbonyl]phenyl]methyl]-2,4(1H,3H)-quinazolinedione |
Synonyms: | IMP4297; JS109 |
分子量: | 478.4510464 |
分子式: | C24H20F2N6O3 |
SMILES: | O=C1NC(N(CC2=CC=C(C(C(N3CCN(CC3)C4=NC=CC=N4)=O)=C2)F)C5=C1C(F)=CC=C5)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Senaparib (IMP4297) 是强效的、选择性的、口服有效的PARP1/2抑制剂。Senaparib (IMP4297) 在动物模型中表现强效的抗肿瘤活性。 |
IC50和靶点: | |
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Solvent & Solubility: |
Meng, X., Lin, X., Jiang, R., et al.Effect of food on the pharmacokinetics of senaparib (IMP4297) in healthy chinese subjectsClin. Drug Investig.42(11),1009-1016(2022)