hSMG-1 inhibitor 11e
Cat. No.：YN290619
| 产品名称: | hSMG-1 inhibitor 11e |
| CAS No.: | 1402452-10-1 |
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| 分子量: | 517.608 |
| 分子式: | C26H27N7O3S |
| SMILES: | C(S(N(C)C)(=O)=O)1=CC(NC2=NC=CC(C3C=CN=C(C4=CC=C(NC(NC)=O)C=C4)C=3)=N2)=CC=C1C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | hSMG-1 inhibitor 11e 是一种有效的选择性的hSMG-1激酶抑制剂，其IC50值 <0.05 nM。hSMG-1 inhibitor 11e 对 hSMG-1 的选择性比mTOR(IC50为 45 nM)，PI3Kα/γ (IC50为 61 nM 和 92 nM) 和 CDK1/CDK2 (IC50为 32 μM 和 7.1 μM) 高 900 倍。 |
| IC50和靶点: | [{name:"hSMG-1:<0.05 nM (IC50)"},{name: "mTOR:45 nM (IC50)"},{name: "PI3Kα:61 nM (IC50)"},{name: "PI3Kγ:92 nM (IC50)"},{name: "CDK1:32 μM (IC50)"},{name: "CDK2:7.1 μM (IC50)"}] |
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