NSC 107512
Cat. No.：YN290627
CAS No. ：141992-47-4
| 产品名称: | NSC 107512 |
| CAS No.: | 141992-47-4 |
| Chemical Name: | 1,4-dimethoxy-9(10H)-acridinethione |
| Synonyms: | |
| 分子量: | 271.33526 |
| 分子式: | C15H13NO2S |
| SMILES: | S=C1C2=C(NC3=C1C(OC)=CC=C3OC)C=CC=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | NSC 625987 是一种特异的高亲和力的CDK4抑制剂，对CDK4:cyclin D1的IC50为 0.2 μM。NSC 625987 对CDK4的选择性是CDK2的 500 倍以上。 |
| IC50和靶点: | [{name:"CDK4/D1:0.2 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Kubo, A., Nakagawa, K., Varma, R.K., et al.The p16 status of tumor cell lines identifies small molecule inhibitors specific for cyclin-dependent kinase 4Clin. Cancer Res.5(12),4279-4286(1999)
Jorda, R., Hendrychová, D., Voller, J., et al.How selective are pharmacological inhibitors of cell-cycle-regulating cyclin-dependent kinases?J. Med. Chem.61(20),9105-9120(2018)
