AKI603
Cat. No.:YN290630
CAS No. :1432515-73-5
产品名称: | AKI603 |
CAS No.: | 1432515-73-5 |
Chemical Name: | |
Synonyms: | AKI603;AKI-603;AKI 603 |
分子量: | 409.45 |
分子式: | C19H23N9O2 |
SMILES: | CN1CCN(CC1)C2=NC(=NC(=C2)NC3=N[NH]C(=C3)C)NC4=CC=C(C=C4)[N;v5](=O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | AKI603 是一种极光激酶 A (AurA) 抑制剂,其IC50值为 12.3 nM,被开发用于克服白血病中 BCR-ABL-T315I 耐药性突变。AKI603 对白血病细胞具有很强的抗增殖活性。 |
IC50和靶点: | [{name:"Aurora A:12.3 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |