Mefuparib hydrochloride
Cat. No.：YN290632
| 产品名称: | Mefuparib hydrochloride |
| CAS No.: | 1449746-00-2 |
| Chemical Name: | |
| Synonyms: | MPH |
| 分子量: | 334.77 |
| 分子式: | C17H16ClFN2O2 |
| SMILES: | O=C(C1=C(OC(C2=CC=C(CNC)C=C2)=C3)C3=CC(F)=C1)N.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Mefuparib hydrochloride (MPH) 是一种具有口服活性的，底物竞争性和选择性的PARP1/2抑制剂，IC50分别为 3.2 nM 和 1.9 nM。Mefuparib hydrochloride 诱导细胞凋亡 (apoptosis)，并在体内外具有显着的抗癌活性。 |
| IC50和靶点: | [{name:"PARP1:3.2 nM (IC50)"},{name: "PARP2:1.9 nM (IC50)"},{name: "TNKS1:1.6 μM (IC50)"},{name: "TNKS2:1.3 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
