KDM2/7-IN-1
Cat. No.：YN310423
| 产品名称: | KDM2/7-IN-1 |
| CAS No.: | 1453071-47-0 |
| Chemical Name: | N-(9-cyclopropyl-1-oxononyl)-N-hydroxy-β-alanine |
| Synonyms: | |
| 分子量: | 285.4 |
| 分子式: | C15H27NO4 |
| SMILES: | O=C(O)CCN(C(CCCCCCCCC1CC1)=O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | KDM2/7-IN-1 (TC-E 5002) 是一种选择性组蛋白去甲基酶KDM2/7亚家族抑制剂 (对于KDM7A、KDM7B、KDM2A、KDM5A、KDM4C、KDM6A和KDM4A，其IC50值分别为 0.2、1.2、6.8、55、83、>100 和 >120 μM)。KDM2/7-IN-1 在体外抑制 HeLa 和 KYSE-150 癌细胞的生长。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Suzuki, T., Ozasa, H., Itoh, Y., et al.Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activityJ. Med. Chem.56(18),7222-7231(2013)
