MSC2504877
Cat. No.：YN290636
CAS No. ：1460286-21-8
| 产品名称: | MSC2504877 |
| CAS No.: | 1460286-21-8 |
| Chemical Name: | |
| Synonyms: | M2912 |
| 分子量: | 282.34 |
| 分子式: | C17H18N2O2 |
| SMILES: | CC1=CC=C2[N]1C=C(NC2=O)C3=CC=C(C=C3)C(C)(C)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MSC2504877 (M2912) 是一种有效的，具有口服活性的tankyrase抑制剂，对 TNKS、TNKS2、PARP1 的 IC50值分别为 0.0007、0.0008、0.54 µM。MSC2504877 增加 AXIN2 和 TNKS 蛋白的表达水平并降低β-catenin蛋白水平。MSC2504877 具有抗肿瘤活性。 |
| IC50和靶点: | [{name:"PARP1:0.54 μM (IC50)"},{name: "TNKS:0.0007 μM (IC50)"},{name: "TNKS2:0.0008 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
