Niraparib tosylate hydrate
Cat. No.：YN290648
| 产品名称: | Niraparib tosylate hydrate |
| CAS No.: | 1613220-15-7 |
| Chemical Name: | |
| Synonyms: | MK-4827 tosylate hydrate |
| 分子量: | 510.609 |
| 分子式: | C26H30N4O5S |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Niraparib (MK-4827) tosylate hydrate 是高效的，具有生物口服利用度的PARP1和PARP2抑制剂，IC50分别为 3.8 nM 和 2.1 nM。Niraparib tosylate hydrate 抑制 DNA 损伤修复，诱导凋亡 (apoptosis) 并具有抗肿瘤活性。 |
| IC50和靶点: | [{name:"PARP-2:2.1 nM (IC50)"},{name: "PARP-1:3.8 nM (IC50)"},{name: "V-PARP:330 nM (IC50)"},{name: "TANK-1:570 nM (IC50)"},{name: "PARP-3:1300 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
