Epiblastin A
Cat. No.：YN290656
CAS No. ：16470-02-3
| 产品名称: | Epiblastin A |
| CAS No.: | 16470-02-3 |
| Chemical Name: | 6-(3-chlorophenyl)-2,4,7-pteridinetriamine |
| Synonyms: | Epiblastin A; AUE; |
| 分子量: | 287.7 |
| 分子式: | C12H10ClN7 |
| SMILES: | NC1=NC2=NC(N)=NC(N)=C2N=C1C3=CC(Cl)=CC=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Epiblastin A 是一种 ATP 竞争性的酪蛋白激酶 1 (CK1) 抑制剂，对 CK1α， CK1δ， 和CK1 ɛ 的IC50分别为 8.9， 0.5，和 4.7 µM。Epiblastin A 通过抑制CK1诱导外胚层干细胞重编程为胚胎干细胞。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Ursu, A., Illich, D.J., Takemoto, Y., et al.Epiblastin A induces reprogramming of epiblast stem cells into embryonic stem cells by inhibition of Casein Kinase 1Cell Chem. Biol.23(4),494-507(2016)
