GSK121
Cat. No.：YN310434
| 产品名称: | GSK121 |
| CAS No.: | 1652591-80-4 |
| Chemical Name: | (3-amino-1-piperidinyl)[1-methyl-2-(1-methyl-1H-indol-2-yl)-1H-benzimidazol-5-yl]-methanone, 2,2,2-trifluoroacetate |
| Synonyms: | |
| 分子量: | 501.5 |
| 分子式: | C23H25N5O • CF3COOH |
| SMILES: | NC1CN(C(C2=CC(N=C(C3=CC(C=CC=C4)=C4N3C)N5C)=C5C=C2)=O)CCC1.FC(F)(C(O)=O)F |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GSK-121 Trifluoroacetate 是选择性的PAD4抑制剂。 |
| IC50和靶点: | |
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Jones, J.E., Causey, C.P., Knuckley, B., et al.Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potentialCurr. Opin. Drug Discov. Devel.12(5),616-627(2009)
Lewis, H.D., Liddle, J., Coote, J.E., et al.Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formationNat. Chem. Biol.11(3),189-191(2015)
