Venadaparib
Cat. No.：YN290657
CAS No. ：1681017-83-3
| 产品名称: | Venadaparib |
| CAS No.: | 1681017-83-3 |
| Chemical Name: | |
| Synonyms: | IDX-1197 |
| 分子量: | 406.45 |
| 分子式: | C23H23FN4O2 |
| SMILES: | FC1=C(C=C(CC2=NNC(=O)C3=CC=CC=C23)C=C1)C(=O)N4CC(CNC5CC5)C4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Venadaparib (IDX-1197) 是一种有效、选择性和具有口服活性的PARP抑制剂，对PARP1和PARP2的IC50分别为 1.4 nM 和 1.0 nM。Venadaparib 对 PARP-5 不敏感。Venadaparib 可防止 DNA 单链断裂 (SSB) 的修复，可用于实体瘤研究。 |
| IC50和靶点: | [{name:"PARP1:1.4 nM (IC50)"},{name: "PARP2:1 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
