TC-E 5003
Cat. No.：YN310437
| 产品名称: | TC-E 5003 |
| CAS No.: | 17328-16-4 |
| Chemical Name: | N,N'-(sulfonyldi-4,1-phenylene)bis[2-chloro]-acetamide |
| Synonyms: | NSC 30176 |
| 分子量: | 401.3 |
| 分子式: | C16H14Cl2N2O4S |
| SMILES: | ClCC(NC1=CC=C(S(C2=CC=C(NC(CCl)=O)C=C2)(=O)=O)C=C1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TC-E 5003 是一种选择性的PRMT1抑制剂，对 hPRMT1 的IC50为 1.5 µM。TC-E 5003 在TLR4信号传导中具有抗炎特性。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Bissinger, E.M., Heinke, R., Spannhoff, A., et al.Acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hPRMT1Bioorg. Med. Chem.19(12),3717-3731(2011)
Prescott, B.Potential antimalarial agents. Derivatives of 4,4'-diaminodiphenylsulfoneInt. Z. Klin. Pharmakol. Ther. Toxikol.4(2),207-211(1971)
