SGC2085 hydrochloride
Cat. No.：YN310444
| 产品名称: | SGC2085 hydrochloride |
| CAS No.: | 1821908-49-9 |
| Chemical Name: | 2S-amino-N-[[4-(3,5-dimethylphenoxy)-3-methylphenyl]methyl]-propanamide, monohydrochloride |
| Synonyms: | |
| 分子量: | 348.9 |
| 分子式: | C19H24N2O2 • HCl |
| SMILES: | CC1=CC(C)=CC(OC2=CC=C(CNC([C@@H](N)C)=O)C=C2C)=C1.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SGC2085 hydrochloride 是一种有效的选择性共激活剂相关精氨酸甲基转移酶 1 (CARM1) 抑制剂，IC50为 50 nM。SGC2085 hydrochloride 还选择性抑制PRMT6，IC50为 5.2 μM，但不抑制其他 PRMT 蛋白。 |
| IC50和靶点: | [{name:"PRMT6:5.2 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Ferreira de Freitas, R., Eram, M.S., Smil, D., et al.Discovery of a potent and selective coactivator associated arginine methyltransferase 1 (CARM1) inhibitor by virtual screeningJ. Med. Chem.59(14),6838-6847(2016)
