Epsilon-V1-2
Cat. No.：YN310445
| 产品名称: | Epsilon-V1-2 |
| CAS No.: | 182683-50-7 |
| Chemical Name: | |
| Synonyms: | ε-V1-2; EAVSLKPT |
| 分子量: | 844 |
| 分子式: | C37H65N9O13 |
| SMILES: | [H]N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N1CCC[C@H]1C(N[C@]([C@@H](C)O)([H])C(O)=O)=O)=O)=O)=O)=O)=O)C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Epsilon-V1-2 (ε-V1-2) 是一种PKCε衍生肽，是一种选择性PKCε抑制剂。Epsilon-V1-2 抑制PKCε的转运，但不抑制 α-，β- 和 δPKC 的转运。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
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Schuster, D.J., Kitto, K.F., Overland, A.C., et al.Protein kinase Cε is required for spinal analgesic synergy between delta opioid and alpha-2A adrenergic receptor agonist pairsJ. Neurosci.33(33),13538-13546(2013)
Thomspon, J.W., Dave, K.R., Saul, I., et al.Epsilon PKC increases brain mitochondrial SIRT1 protein levels via heat shock protein 90 following ischemic preconditioning in ratsPLoS One8(9),1-12(2013)
Obis, T., Besalduch, N., Hurtado, E., et al.The novel protein kinase C epsilon isoform at the adult neuromuscular synapse: Location, regulation by synaptic activity-dependent muscle contraction through TrkB signaling and coupling to ACh releaseMol. Brain,(2015)
