CM-579
Cat. No.：YN310449
| 产品名称: | CM-579 |
| CAS No.: | 1846570-40-8 |
| Chemical Name: | |
| Synonyms: | CM579;CM 579 |
| 分子量: | 492.65 |
| 分子式: | C29H40N4O3 |
| SMILES: | N1C2C(=CC(OC)=C(OCCCN3CCCC3)C=2)C(NCC2CCN(C)CC2)=CC=1C1=CC=C(C)O1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CM-579 是首创的、可逆的，G9a和DNA 甲基转移酶(DNMT)的双抑制剂，其IC50值分别为 16 nM 和32 nM。在多种癌细胞中发挥有效活性作用。 |
| IC50和靶点: | [{name:"DNA Methyltransferase:32 nM (IC50)"},{name: "DNMT1:1.5 nM (Kd)"},{name: "DNMT3A:92 nM (IC50)"},{name: "DNMT3B:1000 nM (IC50)"},{name: "G9a:16 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
