Brepocitinib
Cat. No.：YN310450
| 产品名称: | Brepocitinib |
| CAS No.: | 1883299-62-4 |
| Chemical Name: | |
| Synonyms: | PF-06700841 |
| 分子量: | 389.4 |
| 分子式: | C18H21F2N7O |
| SMILES: | CN1C=C(C=N1)NC2=NC=CC(=N2)N3C[C@H]4CC[C@@H](C3)N4C(=O)[C@@H]5CC5(F)F |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Brepocitinib (PF-06700841) 是一种有效的JAK1和TYK2双重抑制剂，IC50值分别为 17 nM 和 23 nM。Brepocitinib 还分别以IC50值为 77 nM 和 6.49 μM 抑制JAK2和JAK3。 |
| IC50和靶点: | [{name:"JAK1:17 nM (IC50)"},{name: "JAK2:77 nM (IC50)"},{name: "JAK3:6.9 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
