PF-CBP1
Cat. No.：YN310453
| 产品名称: | PF-CBP1 |
| CAS No.: | 1962928-21-7 |
| Chemical Name: | 5-(3,5-dimethyl-4-isoxazolyl)-1-[2-(4-morpholinyl)ethyl]-2-[2-(4-propoxyphenyl)ethyl]-1H-benzimidazole |
| Synonyms: | PF CBP1，PF 06670910，PFCBP1，PF06670910 |
| 分子量: | 488.6 |
| 分子式: | C29H36N4O3 |
| SMILES: | CCCOC(C=C1)=CC=C1CCC2=NC3=CC(C4=C(C)ON=C4C)=CC=C3N2CCN5CCOCC5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PF-CBP1是CREB结合蛋白溴区的高度选择性抑制剂。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Iyer, N.G., Özdag, H., and Caldas, C.p300/CBP and cancerOncogene23,4225-4231(2004)
Kalkhoven, E.CBP and p300: HATs for different occasionsBiochem. Pharmacol.68,1145-1155(2004)
Zeng, L., Zhang, Q., Gerona-Navarro, G., et al.Structural basis of site-specific histone recognition by the bromodomains of human coactivators PCAF and CBP/p300Structure16(4),643-652(2008)
Piatnitski Chekler, E.L., Pellegrino, J.A., Lanz, T.A., et al.Transcriptional profiling of a selective CREB binding protein bromodomain inhibitor highlights therapeutic opportunitiesChem. Biol.22(12),1588-1596(2015)
