OTS186935 trihydrochloride
Cat. No.:YN310463
产品名称: | OTS186935 trihydrochloride |
CAS No.: | 2093401-85-3 |
Chemical Name: | |
Synonyms: | OTS186935;OTS-186935;OTS 186935 |
分子量: | 573.34 |
分子式: | C25H29Cl4N5O2 |
SMILES: | N1(C2C=CN3C=C(C4=CC(Cl)=C(OC)C=C4OC)N=C3C=2)CC[C@@H](NCC2C=CN=CC=2)C1.Cl.Cl.Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | OTS186935 trihydrochloride 是一种有效的蛋白甲基转移酶SUV39H2抑制剂,IC50值为 6.49 nM。OTS186935 trihydrochloride 对小鼠异种移植模型的肿瘤生长有明显的抑制作用,且无明显毒性。OTS186935 trihydrochloride 调节癌细胞中 γ-H2AX 的产生。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |