GSK269962A hydrochloride
Cat. No.：YN290681
| 产品名称: | GSK269962A hydrochloride |
| CAS No.: | 2095432-71-4 |
| Chemical Name: | |
| Synonyms: | GSK 269962 hydrochloride |
| 分子量: | 607.06 |
| 分子式: | C29H30N8O5.HCl |
| SMILES: | CCN1C2=CC(=NC=C2N=C1C3=NON=C3N)OC4=CC=CC(=C4)NC(=O)C5=CC=C(C=C5)OCCN6CCOCC6.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GSK269962A hydrochloride (GSK 269962 hydrochloride) 是一种有效的ROCK抑制剂，作用于重组人ROCK1和ROCK2，IC50分别为 1.6 和 4 nM。GSK269962A hydrochloride 具有抗炎和血管舒张作用。 |
| IC50和靶点: | [{name:"ROCK1:1.6 nM (IC50)"},{name: "ROCK2:4 nM (IC50)"},{name: "RSK1:132 nM (IC50)"},{name: "MSK1:49 nM (IC50)"},{name: "AKT1:955 nM (IC50)"},{name: "AKT2:1350 nM (IC50)"},{name: "AKT3:1510 nM (IC50)"},{name: "CDK2:3500 nM (IC50)"},{name: "GSK3α:1260 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
