Edaglitazone
Cat. No.：YN290687
| 产品名称: | Edaglitazone |
| CAS No.: | 213411-83-7 |
| Chemical Name: | 5-[[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]benzo[b]thien-7-yl]methyl]-2,4-thiazolidinedione |
| Synonyms: | 依格列宗 |
| 分子量: | 464.6 |
| 分子式: | C24H20N2O4S2 |
| SMILES: | CC(OC(C1=CC=CC=C1)=N2)=C2CCOC3=C4C(SC=C4)=C(CC5SC(NC5=O)=O)C=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Edaglitazone 是一种有效，选择性和具有口服活性的PPARγ激动剂，对PPARα和PPARγ的EC50值分别为 35.6 nM 和 1053 nM。Edaglitazone 显示出抗血小板、抗糖尿病和抗高血糖活性。 |
| IC50和靶点: | [{name:"PPARγ:35.6 nM (EC50)"},{name: "PPARα:1053 nM (EC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Fürnsinn, C., Brunmair, B., Meyer, M., et al.Chronic and acute effects of thiazolidinediones BM13.1258 and BM15.2054 on rat skeletal muscle glucose metabolismBr. J. Pharmacol.128(6),1141-1148(1999)
