ATM Inhibitor-1
Cat. No.：YN290688
| 产品名称: | ATM Inhibitor-1 |
| CAS No.: | 2135639-94-8 |
| Chemical Name: | |
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| 分子量: | 492.61 |
| 分子式: | C27H36N6O3 |
| SMILES: | C[C@@H](C1CCOCC1)NC2=C(N=NC3=C2C=C(C=C3)C4=CN=C(C=C4)OCCCN(C)C)C(=O)NC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ATMInhibitor-1 是一种有效、选择性、可口服的ATM抑制剂，IC50值为 0.7 nM，对mTOR(IC50，21 μM)，DNAPK (IC50，2.8 μM)，PI3Kα(IC50，3.8 μM)，PI3Kβ(IC50，10.3 μM)，PI3Kγ(IC50，3 μM) 和PI3Kδ(IC50，0.73 μM) 的作用很弱。ATMInhibitor-1 具有抗肿瘤活性。 |
| IC50和靶点: | [{name:"ATM:0.7 nM (IC50)"},{name: "ATM:2.8 nM (IC50, Cellular assay)"},{name: "mTOR:21 μM (IC50)"},{name: "DNAPK:2.8 μM (IC50)"},{name: "PI3Kα:3.8 μM (IC50)"},{name: "PI3Kβ:10.3 μM (IC50)"},{name: "PI3Kγ:3 μM (IC50)"},{name: "PI3Kδ:0.73 μM (IC50)"}] |
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