AG-270
Cat. No.：YN310474
CAS No. ：2201056-66-6
| 产品名称: | AG-270 |
| CAS No.: | 2201056-66-6 |
| Chemical Name: | 3-(1-cyclohexen-1-yl)-6-(4-methoxyphenyl)-2-phenyl-5-(2-pyridinylamino)-pyrazolo[1,5-a]pyrimidin-7(4H)-one |
| Synonyms: | AG-270; AG270; AG 270 |
| 分子量: | 489.56788 |
| 分子式: | C30H27N5O2 |
| SMILES: | O=C1C(C2=CC=C(OC)C=C2)=C(NC3=C(C4=CCCCC4)C(C5=CC=CC=C5)=NN13)NC6=CC=CC=N6 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AG-270 是非竞争性的、首创的、可逆的、具有口服活性的MAT2A变构抑制剂，其IC50值为 14 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Konteatis, Z., Travins, J.G., S., Marjon, K., et al.Discovery of AG-270, a first-in-class oral MAT2A inhibitor for the treatment of tumors with homozygous MTAP deletionJ. Med. Chem.64(8),4430-4449(2021)
