JH-XI-10-02
Cat. No.：YN290694
CAS No. ：2209085-22-1
| 产品名称: | JH-XI-10-02 |
| CAS No.: | 2209085-22-1 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 920.161 |
| 分子式: | C53H69N5O9 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | JH-XI-10-02 是由Cereblon配体和CDK配体相连的PROTAC，是一种高效的选择性PROTACCDK8降解剂，IC50值为 159 nM。JH-XI-10-02 降解CDK8蛋白，但对其 mRNA 水平没有影响。JH-XI-10-02 对CDK19无作用。 |
| IC50和靶点: | [{name:"CDK8:159 nM (IC50)'}, 'Cereblon'] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
