Bractoppin
Cat. No.：YN290705
CAS No. ：2290527-07-8
| 产品名称: | Bractoppin |
| CAS No.: | 2290527-07-8 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 414.474 |
| 分子式: | C25H23FN4O |
| SMILES: | O=C(C1C=C2C(NC(=N2)C2C=CC=CC=2)=CC=1)N1CCN(CC2C(F)=CC=CC=2)CC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Bractoppin 是一种有效的BRCA1 (t)BRCT domain识别磷酸肽的选择性抑制剂 (IC50: 74 nM)。Bractoppin 减少 BRCA1 对 DNA 断裂片段的招募，进而抑制损伤诱导的 G2 期阻滞和重组酶RAD51的组装。Bractoppin 优先抑制 BRCA1 -tBRCT 依赖的 DNA 损伤。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
