RBN-3143
Cat. No.：YN290710
CAS No. ：2360853-16-1
| 产品名称: | RBN-3143 |
| CAS No.: | 2360853-16-1 |
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| 分子量: | 449.54 |
| 分子式: | C22H28FN3O4S |
| SMILES: | O=C1NC(CSC2CCOCC2)=NC3=CC(OCC4CCN(CC4)C(C)=O)=CC(F)=C13 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | RBN-3143 是一种有效的 NAD+ 竞争性催化PARP14抑制剂，IC50值为 4 nM。 RBN-3143 抑制PARP14介导的 ADP-核糖基化并稳定细胞系中的PARP14。 RBN-3143 用于肺部炎症研究。 |
| IC50和靶点: | [{name:"PARP14:4 nM (IC50)"},{name: "PARP10:1600 nM (IC50)"},{name: "PARP15:4200 nM (IC50)"},{name: "PARP4:42700 nM (IC50)"},{name: "PARP3:>100000 nM (IC50)"},{name: "PARP2:>100000 nM (IC50)"},{name: "PARP1:>100000 nM (IC50)"}] |
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